hrp0097p2-88 | Multisystem Endocrine Disorders | ESPE2023

A glimpse of the presentation of Pseudohypoparathyroidism in children.A Case series from a tertiary care Pediatric Endocrine center in Sri Lanka.

Gamage Dilhara , Jayasundara Imalka , Siriwardana Dinendra , Atapattu Navoda

Background: Pseudohypoparathyroidism (PHP) is a condition primarily caused by impaired hormonal signaling through the stimulatory G protein (G2 alpha) for the activation of adenyl cyclase, which is coupled to G protein receptors(1). This occurs due to the molecular defects in the receptors related to the alpha subunit. (1–3). The condition results in resistance to Parathyroid hormone (PTH) and other hormones. Less than 60 cases have been reported worldwi...

hrp0095p2-19 | Adrenals and HPA Axis | ESPE2022

A case series on Adrenal Cortical Tumors in Children, Experience from Colombo, Sri Lanka

Naotunna Randika , Siriwardana Dinendra , Gamage Senani , Lakmini Chamila , Gunaratna Sadani , Atapattu Chamidri Navoda

Introduction: Paediatric adrenocortical tumors (ACT) include both benign adenomas and highly virulent malignant tumors. However, it is very rare among children. The aim of this study is to evaluate the clinicopathological data of children presented with ACT and to assess the survival.Methods: This is a retrospective cohort study which includes patients diagnosed with ACT from August 2020 to July 2021 and followed up at L...